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KMID : 0361420130370010127
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Journal of Korean Academy of Rehabilitation Medicine
2013 Volume.37 No. 1 p.127 ~ p.132
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Motor Axonal Neuropathy Associated With Idiopathic CD4+ T-Lymphocytopenia
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Yi Tae-Im
Kim Bo-Ra
Han In-Soo
Kim Bo-Kyoung
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Abstract
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Idiopathic CD4+ T-lymphocytopenia is a rare immune disorder characterized by an unexplained deficit of CD4+ T cells and results in various opportunistic infections. Herein, we report a case of new onset weakness in a 10-year-old boy secondary to motor axonal neuropathy associated with idiopathic CD4+ T-lymphocytopenia. The patient was referred to rehabilitation for an evaluation of progressive weakness involving all four limbs. A subsequent nerve conduction study and needle electromyography identified motor axonal neuropathy. At that time, laboratory studies specific to the differential diagnosis of motor axonal neuropathy were performed; however, the abnormality noted was a decreased CD4+ T-lymphocyte count. Motor axonal neuropathy represents an uncommon manifestation of idiopathic CD4+ T-lymphocytopenia and is probably associated with an underlying immune process.
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KEYWORD
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Axonal neuropathy, Idiopathic CD4-positive T-lymphocytopenia
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